abstract：OBJECTIVE:• o determine differences in surgical outcomes by surgical approach during a period of rapid adoption of minimally invasive surgical approaches in radical prostatectomy. PATIENTS AND METHODS:• We identified 19 542 men undergoing minimally invasive (MIRP), perineal (PRP), and retropubic (RRP) radical prostate...

journal_title：BJU international

authors： Williams SB,Prasad SM,Weinberg AC,Shelton JB,Hevelone ND,Lipsitz SR,Hu JC

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To determine whether the density of CD4(+) and CD8(+) T-lymphocytes in a transrectal ultrasonography (TRUS) biopsy of the prostate can be used to predict the progression of lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH). PATIENTS AND METHODS:In total, 100 patients were randomly sel...

journal_title：BJU international

authors： Lamb AD,Qadan M,Roberts S,Timlin H,Vowler SL,Campbell FM,Grigor K,Bartlett JM,McNeill SA

更新日期：2011-07-01 00:00:00

abstract：:What is known on the subject? and What does the study add? Substantial experience of the outcomes has been gathered regarding the acute and sub-acute experience with various types of corrective procedures for POP. These include long-term POP correction as well as more recent recognition of improvement in functional di...

journal_title：BJU international

authors： Gomelsky A,Penson DF,Dmochowski RR

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:• To compare outcomes of hilar clamping and non-hilar clamping partial nephrectomy for tumours involving a solitary functional kidney. PATIENTS AND METHODS:• Between 1990 and 2009, 104 partial nephrectomies, excluding bench and autotransplant procedures, were performed on solitary functional kidneys. • An in...

journal_title：BJU international

authors： Wszolek MF,Kenney PA,Lee Y,Libertino JA

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:• To report outcomes for patients with localized prostate cancer managed using a watchful waiting strategy at an American centre and to explore factors that have triggered intervention. PATIENTS AND METHODS:• From 1991 to 2005, 218 patients diagnosed with untreated localized prostate cancer were followed at ...

journal_title：BJU international

authors： Coen JJ,Feldman AS,Smith MR,Zietman AL

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:• To investigate the oncological efficacy of retroperitoneal laparoscopic radical nephrectomy (RLRN) compared with transperitoneal laparoscopic radical nephrectomy (TLRN) for the management of clear-cell renal cell carcinoma (RCC). PATIENTS AND METHODS:• With emphasis on survival and disease recurrence, a re...

journal_title：BJU international

authors： Ha US,Hwang TK,Kim YJ,Oh TH,Jeon YS,Lee W,Lim JS,Lee TY,Choi Y,Park SK,Byun SS

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:• To compare the influence of a 4-week course of empirical antimicrobial therapy or observation on the prostate-specific antigen (PSA) levels of asymptomatic patients with a raised baseline PSA. • To identify whether a decrease in PSA can predict the risk of prostate cancer (PCa) detection on prostate biopsy...

journal_title：BJU international

authors： Heldwein FL,Teloken PE,Hartmann AA,Rhoden EL,Teloken C

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:• Obesity induced by high-fat diet (HFD) is one of the most important risk factor for the development of erectile dysfunction (ED) in man. This study aimed to characterize the ED resulting from obesity associated with HFD in mice. MATERIALS AND METHODS:• C57BL/6 mice fed for 10 weeks with either HFD to induc...

journal_title：BJU international

authors： Toque HA,da Silva FH,Calixto MC,Lintomen L,Schenka AA,Saad MJ,Zanesco A,Antunes E

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:• To evaluate the combination of multiple magnetic resonance imaging (MRI) techniques, including T2-weighted imaging (T2W), dynamic contrast-enhanced imaging (DCE) and diffusion-weighted imaging (DWI), for the detection and localization of prostate cancer. PATIENTS AND METHODS:• In all, 57 patients underwent...

journal_title：BJU international

authors： Delongchamps NB,Rouanne M,Flam T,Beuvon F,Liberatore M,Zerbib M,Cornud F

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:• To investigate the feasibility of tissue-engineered corpus cavernosum (TECC) with muscle-derived stem cells (MDSCs) as seed cells and determine the growth potential in vivo. MATERIALS AND METHODS:• Acellular corporal collagen matrices (ACCMs) were obtained from adult rabbit penis by a cell removal procedur...

journal_title：BJU international

authors： Ji C,Min F,Liang W,Chen Y,Pan S,Bin L,Chen S,Wei Z,He T,Gu Y,Zhang J

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:• To investigate the relationship between pretreatment testosterone levels and pathological specimen characteristics, by prospectively examining serum androgen concentrations in a well-studied cohort of patients who underwent radical prostatectomy (RP) for localized prostate cancer. PATIENTS AND METHODS:• A ...

journal_title：BJU international

authors： Xylinas E,Ploussard G,Durand X,Fabre A,Salomon L,Allory Y,Vordos D,Hoznek A,Abbou CC,de la Taille A

更新日期：2011-05-01 00:00:00

abstract：:To assess the evidence for the concept that the androgen receptor of prostate cancer (PCa) cells becomes saturated when testosterone values exceed castrate levels, so that testosterone administration in hypogonadal men with untreated PCa does not stimulate tumour growth. To propose basic criteria for administration of...

journal_title：BJU international

authors： Morales A

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:• To investigate the role of c-kit-positive interstitial cells (ICCs) in mediating muscarinic receptor-induced phasic contractions of isolated bladder strips from streptozotocin(STZ)-induced diabetic rats and to confirm the expression and location of ICCs in the rat bladder. MATERIALS AND METHODS:• Bladders ...

journal_title：BJU international

authors： Vahabi B,McKay NG,Lawson K,Sellers DJ

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:•  To systematically review the current literature concerning perioperative, functional and oncological outcomes reported after open and minimally invasive prostate cancer surgery specifically from institutions within Australasia. MATERIALS AND METHODS:•  Four electronic databases were searched to identify s...

journal_title：BJU international

authors： Cathcart P,Murphy DG,Moon D,Costello AJ,Frydenberg M

更新日期：2011-04-01 00:00:00

abstract：:What's known on the subject? and What does the study add? • Six targeted agents--sorafenib, sunitinib, pazopanib, bevacizumab, temsirolimus and everolimus--have been approved for the treatment of advanced renal cell carcinoma (RCC) based on evidence from large randomized controlled trials (RCTs). However, no head-to-h...

journal_title：BJU international

authors： Bellmunt J,Eisen T,Szczylik C,Mulders P,Porta C

更新日期：2011-04-01 00:00:00

abstract：UNLABELLED:Study Type--Therapy (case series) Level of Evidence 4. What's known on the subject? and What does the study add? Previous reports showed controversial evidence supporting the role of sex steroids, mainly testosterone, in the etiology and pathogenesis of prostate cancer (PCa). The bioavailability of sex stero...

journal_title：BJU international

authors： Salonia A,Gallina A,Briganti A,Zanni G,Suardi N,Capitanio U,Colombo R,Bertini R,Freschi M,Guazzoni G,Rigatti P,Montorsi F

更新日期：2011-04-01 00:00:00

abstract：:Docetaxel-based therapy is established as the standard first-line chemotherapy in patients with metastatic castration-resistant prostate cancer (mCRPC), based on results from two landmark Phase III studies. However, prognosis remains poor, with a median survival of less than 2 years. There is no standard of care for p...

journal_title：BJU international

authors： Bracarda S,Logothetis C,Sternberg CN,Oudard S

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:• To investigate the influence of baseline variables on the 4-year incidence of acute urinary retention (AUR), benign prostatic hyperplasia (BPH)-related surgery and overall clinical progression in men treated with tamsulosin, dutasteride, or a combination of both. PATIENTS AND METHODS:• The 4-year Combinati...

journal_title：BJU international

authors： Roehrborn CG,Barkin J,Siami P,Tubaro A,Wilson TH,Morrill BB,Gagnier RP

更新日期：2011-03-01 00:00:00

abstract：:OBJECTIVE • To evaluate a novel technique to lower positive surgical margin rates while preserving as much of the neurovascular bundles as possible during nerve-sparing robotic prostatectomy. MATERIALS AND METHODS • In situ intraoperative frozen section (IFS) was performed during robotic-assisted laparoscopic prostate...

journal_title：BJU international

authors： Lavery HJ,Xiao GQ,Nabizada-Pace F,Mikulasovich M,Unger P,Samadi DB

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:• To evaluate the functional and morphological outcome after open pyeloplasty for ureteropelvic junction obstruction (UPJO) with huge renal pelvis. PATIENTS AND METHODS:• A retrospective review of all cases who underwent pyeloplasty for huge renal pelvis was conducted. • Records were evaluated with respect t...

journal_title：BJU international

authors： Sarhan O,Helmy T,Abou-El Ghar M,Baky MA,El-Assmy A,Dawaba M

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:• To evaluate the safety and efficacy of once-daily trospium chloride extended release (ER) in overactive bladder syndrome (OAB) in subjects aged ≥ 75 years. SUBJECTS AND METHODS:• The analysis included subjects ≥ 75 years of age with OAB. • A subgroup analysis of pooled data was performed for subjects aged ...

journal_title：BJU international

authors： Sand PK,Johnson Ii TM,Rovner ES,Ellsworth PI,Oefelein MG,Staskin DR

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of weight loss and time post laparoscopic gastric banding surgery (LGB) on urinary and sexual function. MATERIALS AND METHODS:653 females and 145 males who underwent LGB over the last 10 years at a single centre in Australia were contacted by post and asked to complete validated qu...

journal_title：BJU international

authors： Ranasinghe WK,Wright T,Attia J,McElduff P,Doyle T,Bartholomew M,Hurley K,Persad RA

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinicopathological outcomes for patients with clinical T2 (cT2) urothelial carcinoma treated with radical cystectomy (RC) without neoadjuvant chemotherapy (NC). PATIENTS AND METHODS:We identified 212 patients with cT2 tumours who underwent RC at our institution without NC. Pathological asses...

journal_title：BJU international

authors： Canter D,Long C,Kutikov A,Plimack E,Saad I,Oblaczynski M,Zhu F,Viterbo R,Chen DY,Uzzo RG,Greenberg RE,Boorjian SA

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To compare extracorporeal shockwave lithotripsy (ESWL) and ureteroscopy (URS) as first-line treatments for patients with distal ureteric stones. PATIENTS AND METHODS:In all, 273 patients with single, monolateral, radiopaque, distal ureteric stones of 0.5-1.5 cm were enrolled in a prospective randomized trial...

journal_title：BJU international

authors： Verze P,Imbimbo C,Cancelmo G,Creta M,Palmieri A,Mangiapia F,Buonopane R,Mirone V

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To determine the adequacy of T2 prostate cancer (PCa) sub-staging as an independent Predictor of biochemical disease-free survival (bDFS) after radical prostatectomy. MATERIALS AND METHODS:The Duke Prostate Center database was queried for patients who underwent radical prostatectomy between 1988 and 2007 and...

journal_title：BJU international

authors： Caso JR,Tsivian M,Mouraviev V,Polascik TJ,Moul JW

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:To prospectively evaluate the accuracy of transvesical contrast-enhanced ultrasound (CEUS) as an alternative method for the detection of anastomotic leakage after radical retropubic prostatectomy (RRP) in comparison with the current standard method of conventional retrograde cystography (CG). PATIENTS AND...

journal_title：BJU international

authors： Schoeppler GM,Buchner A,Zaak D,Khoder W,Staehler M,Stief CG,Reiser MF,Clevert DA

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To determine if antibiotic prophylaxis is required for intradetrusor botulinum toxin A (BoNT-A) injections. PATIENTS AND METHODS:This was a prospective non-randomized study. Inclusion criteria were adult patients with neurogenic detrusor overactivity who failed anticholinergic-based first-line treatment and ...

journal_title：BJU international

authors： Mouttalib S,Khan S,Castel-Lacanal E,Guillotreau J,De Boissezon X,Malavaud B,Marque P,Rischmann P,Gamé X

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the oncological outcomes of patients with specimen Gleason 8 and 9 prostate cancers and to determine factors that predict biochemical recurrence-free survival (BCRFS) after robot-assisted radical prostatectomy (RARP). PATIENTS AND METHODS:Of 4156 patients who underwent RARP from January 2001 to 2...

journal_title：BJU international

authors： Wambi CO,Siddiqui SA,Krane LS,Agarwal PK,Stricker HJ,Peabody JO

更新日期：2010-12-01 00:00:00

abstract：:OBJECTIVE To assess the effect of age and comorbidity on short-term complications, long-term continence and oncological outcome after laparoscopic radical prostatectomy (LRP) for localized prostate cancer. PATIENTS AND METHODS In all, 2048 consecutive men underwent LRP for localized prostate cancer in one institution....

journal_title：BJU international

authors： Sanchez-Salas R,Prapotnich D,Rozet F,Mombet A,Cathala N,Barret E,Galiano M,Cathelineau X,Vallancien G

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that three-dimensional hypofractionated radiotherapy (3D-HFRT) is well tolerated and not worse than 3-D conventional RT (3D-CRT) for oncological outcome. PATIENTS AND METHODS:In all, 162 men with hystologically confirmed prostate adenocarcinoma were included in the analysis. In all, 82...

journal_title：BJU international

authors： Di Staso M,Bonfili P,Gravina GL,Di Genesio Pagliuca M,Franzese P,Buonopane S,Osti MF,Valeriani M,Festuccia C,Enrici RM,Tombolini V

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To study guideline recommendation (GR)-concordance rates of treatment in elderly patients with urothelial carcinoma of the bladder (UCB) and to identify predictors of survival. PATIENTS AND METHODS:The records of 206 consecutive patients aged ≥ 75 years (median age 79 years; range 75-95) were reviewed. All p...

journal_title：BJU international

authors： Bolenz C,Ho R,Nuss GR,Ortiz N,Raj GV,Sagalowsky AI,Lotan Y

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To investigate the potential role of platelet-derived growth factor-AA (PDGF-AA) and the PDGF-α receptor as prognostic markers in Wilms' tumour. PATIENTS AND METHODS:The expression of PDGF-AA and PDGF-α were investigated using immunohistochemical analysis of 62 Wilms' tumours. Patients were treated with chem...

journal_title：BJU international

authors： Ghanem M,Nijman R,Safan M,van der Kwast T,Vansteenbrugge G

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To identify the outcome of nephrectomy and predictors of hypertension (HTN) resolution in children with poorly functioning unilateral kidneys (differential renal function, DRF of < 15%), as concurrent HTN is often an indication for nephrectomy. PATIENTS AND METHODS:Over a 7.5-year period, a single centre ret...

journal_title：BJU international

authors： El-Hout Y,Licht C,Pippi Salle JL,Ngan BY,Bagli DJ,Lorenzo AJ,Farhat WA

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To examine the effect of short-course androgen-suppression therapy (AST) before brachytherapy on all-cause mortality (ACM) rates, stratified by the presence or absence of a history of myocardial infarction (MI) or stroke. AST is used to reduce prostate size to enable men with favourable-risk prostate cancer t...

journal_title：BJU international

authors： Hayes JH,Chen MH,Moran BJ,Braccioforte MH,Dosoretz DE,Salenius S,Katin MJ,Ross R,Choueiri TK,D'Amico AV

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:to investigate the effect of menopausal transition and age on symptoms of urinary incontinence in midlife. SUBJECTS AND METHODS:the study included a nationally representative cohort of 1211 women followed up since their birth in 1946 and annually from 48-54 years; their menopausal transition status and sympt...

journal_title：BJU international

authors： Mishra GD,Cardozo L,Kuh D

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To determine whether robotic-assisted laparoscopic radical prostatectomy (RALP) is associated with a lower transfusion rate than radical retropubic prostatectomy (RRP). PATIENTS AND METHODS:In this cohort study, we evaluated 1244 consecutive patients who underwent RALP (830) or RRP (414) between June 2003 an...

journal_title：BJU international

authors： Kordan Y,Barocas DA,Altamar HO,Clark PE,Chang SS,Davis R,Herrell SD,Baumgartner R,Mishra V,Chan RC,Smith JA Jr,Cookson MS

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To analyse our long-term oncological outcomes with active surveillance in patients with positive surgical margins (PSMs) after nephron-sparing surgery (NSS) for renal cell carcinoma (RCC), as this situation is a difficult therapeutic dilemma. PATIENTS AND METHODS:We performed open NSS for renal masses with f...

journal_title：BJU international

authors： Lopez-Costea MA,Fumadó L,Lorente D,Riera L,Miranda EF

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a deep and narrow pelvis on apical positive surgical margins (PSM) at radical prostatectomy (RP), controlling for other clinical and pathological variables and surgical approach, i.e. open retropubic (RRP) vs laparoscopic (LRP), as apical dissection is expected to be more challengin...

journal_title：BJU international

authors： Matikainen MP,von Bodman CJ,Secin FP,Yunis LH,Vora K,Guillonneau B,Laudone V,Eastham JA,Scardino PT,Akin O,Rabbani F

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To determine whether conformity to standard recommendations of retroperitoneal lymph node dissection (RPLND) after chemotherapy for testicular and primary retroperitoneal nonseminomatous germ cell tumours (NSGCT) and completeness of surgical excision have an effect on oncological outcome. PATIENTS AND METHOD...

journal_title：BJU international

authors： Fléchon A,Tavernier E,Boyle H,Meeus P,Rivoire M,Droz JP

更新日期：2010-09-01 00:00:00

abstract：:Laparoendoscopic single-site surgery (LESS) and natural orifice transluminal endoscopic surgery (NOTES™) are new approaches to minimally invasive surgery. A number of technical challenges need to be overcome and new developments of equipment are required before widespread acceptance of either modality occurs. In this ...

journal_title：BJU international

authors： Sawyer MD,Ponsky LE

更新日期：2010-09-01 00:00:00